Significance of mononuclear phagocytes in IgA nephropathy

IgA Nephropathy and Significance of Immunostaining Data

iga nephropathy and significance of immunostaining data

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The Differentiation of Mononuclear Phagocytes

The in vitro differentiation of homogeneous populations of monocyte-like cells from the unstimulated mouse peritoneal cavity is described. Under the conditions employed, a progressive increase in cell size occurs without significant cell division. This process is characterized morphologically by the accumulation of phase-dense and neutral red-positive granules, mitochondria, and lipid droplets....

Functional Polarization of Mononuclear Phagocytes

Functional Polarization of Mononuclear Phagocytes Mononuclear phagocyte (MP) encompass bone marrow precursor cells and peripheral blood monocytes that, after a very short time (1–2 days), migrate into the different organs and tissues. Under the influence of the different microenvironments, recently migrated monocytes give rise to a variety of MP subtypes, including mucosal macrophages, dendriti...

IgA nephropathy.

A great interest in IgA nephropathy was demonstrated in the last few years. Unfortunately, a complete picture of this chronic disease should not yet been made. The article deals with 7 patients with IgA nephropathy treated in our Institute. The following characteristics were examined during a long period of time (1-17 years): clinical picture, course of the disease, clinical and morphologic cor...